BDBM603953 (Rac)-trans-3-fluoropropyl 2-ethyl-2-[[6-[[-2-(hydroxymethyl)cyclopropyl]methoxy]-5-[3-(p-tolylsulfonyloxy)azetidin-1-yl]pyridine-2-carbonyl]amino]butanoate::US11655243, Example 31

SMILES CCC(CC)(NC(=O)c1ccc(N2CC(C2)OS(=O)(=O)c2ccc(C)cc2)c(OC[C@H]2C[C@@H]2CO)n1)C(=O)OCCCF

InChI Key InChIKey=MKUGCTURZCGMDL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 603953   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM603953(US11655243, Example 31 | (Rac)-trans-3-fluoropropy...)
Affinity DataKi:  11.7nMAssay Description:The affinity of the compounds of the invention for cannabinoid CB1 receptors was determined using recommended amounts of membrane preparations (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
Go to US Patent