BDBM603921 2-[[4-[6-[(4-Cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-2,6-difluoro-phenyl]methyl]-3-[(2S)-oxetan-2-ylmethyl]benzimidazole-5-carboxylic Acid::US11655242, Example 4

SMILES OC(=O)c1ccc2nc(Cc3c(F)cc(cc3F)-c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2c1

InChI Key InChIKey=YHWOWBZYTVVUQA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 603921   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Eli Lilly

US Patent

LigandBDBM603921(US11655242, Example 4 | 2-[[4-[6-[(4-Cyano-2-fluor...)Copy SMILESCopy InChI

Affinity DataIC50: 5.41E+3nMAssay Description:PDE10A1 enzyme activities are measured with a yittrium silicate based scintillation proximity assay (SPA) that detects radioactive nucleotide monopho...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/26/2023
Entry Details
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