BDBM603919 2-[[4-[6-[(4-Cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-2-fluoro-5-methyl-phenyl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic Acid::US11655242, Example 2::US20250066338, Ref Comp D

SMILES Cc1cc(Cc2nc3ccc(cc3n2C[C@@H]2CCO2)C(O)=O)c(F)cc1-c1cccc(OCc2ccc(cc2F)C#N)n1

InChI Key InChIKey=QZQFEJHDNYVBKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 603919   

LigandPNGBDBM603919(US11655242, Example 2 | 2-[[4-[6-[(4-Cyano-2-fluor...)
Affinity DataIC50: 7.43E+3nMAssay Description:PDE10A1 enzyme activities are measured with a yittrium silicate based scintillation proximity assay (SPA) that detects radioactive nucleotide monopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
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TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Astrazeneca

US Patent
LigandPNGBDBM603919(US11655242, Example 2 | 2-[[4-[6-[(4-Cyano-2-fluor...)
Affinity DataIC50: 5.00E+3nMAssay Description:Evaluation of the effects of compounds on the activity of the human phosphodiesterase-3A is quantified by measuring the formation of 5′AMP from cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent