BDBM603918 2-[[4-[6-[(4-Cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-3-methyl-phenyl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic Acid::US11655242, Example 1

SMILES Cc1cc(Cc2nc3ccc(cc3n2C[C@@H]2CCO2)C(O)=O)ccc1-c1cccc(OCc2ccc(cc2F)C#N)n1

InChI Key InChIKey=AHNWKZGQCCULJE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 603918   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Eli Lilly

US Patent

LigandBDBM603918(US11655242, Example 1 | 2-[[4-[6-[(4-Cyano-2-fluor...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:PDE10A1 enzyme activities are measured with a yittrium silicate based scintillation proximity assay (SPA) that detects radioactive nucleotide monopho...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/26/2023
Entry Details
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