BDBM60311 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carboxylic acid ethyl ester::4,5-diketo-2-methyl-3H-benz[e]indole-1-carboxylic acid ethyl ester::MLS000701140::SMR000226436::cid_1736294::ethyl 2-methyl-4,5-bis(oxidanylidene)-3H-benzo[e]indole-1-carboxylate::ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carboxylate::ethyl 2-methyl-4,5-dioxo-4,5-dihydro-3H-benzo[e]indole-1-carboxylate

SMILES CCOC(=O)c1c(C)[nH]c2c1-c1ccccc1C(=O)C2=O

InChI Key InChIKey=OIWQLSMNVRMWRN-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 60311   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataIC50: 915nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataEC50:  1.57E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataIC50: 2.37E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataIC50: 2.37E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataIC50: 2.70E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetPlectin(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM60311(ethyl 2-methyl-4,5-dioxo-3H-benzo[e]indole-1-carbo...)
Affinity DataIC50: 2.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay