BDBM603081 US11649255, Example 109::US11649255, Example 56

SMILES Cc1c(F)c(F)c2[nH]ncc2c1-c1ccc2nc(NC(=O)[C@@H]3C[C@@H]3F)sc2c1

InChI Key InChIKey=XMJJROVVXOMWRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 603081   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM603081(US11649255, Example 56 | US11649255, Example 109)
Affinity DataIC50: 100nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM603081(US11649255, Example 56 | US11649255, Example 109)
Affinity DataIC50: 100nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent