BDBM603074 US11649255, Example 50

SMILES F[C@H]1CC1C(=O)Nc1nc2ccc(cc2s1)-c1c(c(F)cc2[nH]ncc12)C(F)(F)F

InChI Key InChIKey=UOGSXPGGCBSIEC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 603074   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
1St Biotherapeutics

US Patent

LigandBDBM603074(US11649255, Example 50)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:HPK1 kinase activity was measured by Promega's ADP-Glo kinase assay. In this assay, 5 ng of recombinant human HPK1 (signalchem) is incubated with...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/19/2023
Entry Details
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