BDBM602698 6-Chloro-3-[1-[3,6-dimethyl-4- oxo-2-(1-piperidyl)chromen-8- yl]ethylamino]pyridine-2- carboxylic acid::US11649227, Example 305::US20230286960, Example 305

SMILES CC(Nc1ccc(Cl)nc1C(O)=O)c1cc(C)cc2c1oc(N1CCCCC1)c(C)c2=O

InChI Key InChIKey=JDBYUIJSHHXGKV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602698   

LigandPNGBDBM602698(US11649227, Example 305 | 6-Chloro-3-[1-[3,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602698(US11649227, Example 305 | 6-Chloro-3-[1-[3,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602698(US11649227, Example 305 | 6-Chloro-3-[1-[3,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM602698(US11649227, Example 305 | 6-Chloro-3-[1-[3,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent