BDBM602688 2- [[(1R)-1- [3 ,6-dimethyl-4-oxo-2- [(3R)-3-phenylpyrrolidin-1- yl]chromen-8-yl]ethyl]amino]benzoic acid::US11649227, Example 286::US20230286960, Example 286

SMILES C[C@@H](Nc1ccccc1C(O)=O)c1cc(C)cc2c1oc(N1CC[C@@H](C1)c1ccccc1)c(C)c2=O

InChI Key InChIKey=LCAYWFPKAXHESA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602688   

LigandPNGBDBM602688(US11649227, Example 286 | 2- [[(1R)-1- [3 ,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602688(US11649227, Example 286 | 2- [[(1R)-1- [3 ,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602688(US11649227, Example 286 | 2- [[(1R)-1- [3 ,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM602688(US11649227, Example 286 | 2- [[(1R)-1- [3 ,6-dimet...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent