BDBM602685 2-[1-(2-Isoindolin-2-yl-3,6- dimethyl-4-oxo-chromen-8- yl)ethylamino]benzoic acid, Isomer 1::US11649227, Example 265::US20230286960, Example 265

SMILES CC(Nc1ccccc1C(O)=O)c1cc(C)cc2c1oc(N1Cc3ccccc3C1)c(C)c2=O

InChI Key InChIKey=JDYCPMDZQGACFN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602685   

LigandPNGBDBM602685(US11649227, Example 265 | 2-[1-(2-Isoindolin-2-yl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602685(US11649227, Example 265 | 2-[1-(2-Isoindolin-2-yl-...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602685(US11649227, Example 265 | 2-[1-(2-Isoindolin-2-yl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM602685(US11649227, Example 265 | 2-[1-(2-Isoindolin-2-yl-...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent