BDBM602674 2-[1-[6-Methyl-4-oxo-2-(1- phenyl-1,6- diazaspiro[3.3]heptan-6- yl)chromen-8- yl]ethylamino]benzoic acid 2,2,2-trifluoroacetic acid, Isomer 1::US11649227, Example 203::US20230286960, Example 203

SMILES CC(Nc1ccccc1C(O)=O)c1cc(C)cc2c1oc(cc2=O)N1CC2(CCN2c2ccccc2)C1

InChI Key InChIKey=KZFSANGCOTWREH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602674   

LigandPNGBDBM602674(US11649227, Example 203 | 2-[1-[6-Methyl-4-oxo-2-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602674(US11649227, Example 203 | 2-[1-[6-Methyl-4-oxo-2-(...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602674(US11649227, Example 203 | 2-[1-[6-Methyl-4-oxo-2-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM602674(US11649227, Example 203 | 2-[1-[6-Methyl-4-oxo-2-(...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent