BDBM602672 2-[1-[2-[3-(1,1- Difluoroethyl)azetidin-l-yl]-6- methyl-4-oxo-chromen-8- yl]ethylamino]benzoic acid 2,2,2-trifluoroacetic acid::US11649227, Example 189::US20230286960, Example 189

SMILES CC(Nc1ccccc1C(O)=O)c1cc(C)cc2c1oc(cc2=O)N1CC(C1)C(C)(F)F

InChI Key InChIKey=UEJOHUNQPIZFFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 602672   

LigandPNGBDBM602672(US11649227, Example 189 | 2-[1-[2-[3-(1,1- Difluor...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602672(US11649227, Example 189 | 2-[1-[2-[3-(1,1- Difluor...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent

LigandPNGBDBM602672(US11649227, Example 189 | 2-[1-[2-[3-(1,1- Difluor...)
Affinity DataIC50: 3.00E+3nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM602672(US11649227, Example 189 | 2-[1-[2-[3-(1,1- Difluor...)
Affinity DataIC50: 500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent