BDBM602247 4-(4-(((R)-1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)amino)-7-methoxy-2- methylpyrido[2,3-d]pyrimidin-6-yl)-1- iminohexahydro-1lambda6-thiopyran 1-oxide::BDBM602248::US11648254, Compound 153

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1[C@H]1CCS(=N)(=O)CC1

InChI Key InChIKey=CCMBLVPBKOZOTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 602247   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602247(BDBM602248 | US11648254, Compound 153 | 4-(4-(((R)...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602247(BDBM602248 | US11648254, Compound 153 | 4-(4-(((R)...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent