BDBM602242 4-(4-(((R)-1-(3-(difluoro((S)- tetrahydrofuran-2- yl)methyl)-2-fluorophenyl)ethyl)amino)-7- methoxy-2-methylpyrido[2,3-d]pyrimidin- 6-yl)tetrahydro-2H-thiopyran 1,1-dioxide::US11648254, Compound 148

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(c3F)C(F)(F)C3CCCO3)c2cc1C1CCS(=O)(=O)CC1

InChI Key InChIKey=QGVOPAIPASPJAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602242   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602242(US11648254, Compound 148 | 4-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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