BDBM602217 N-((1S,3s)-3-(4-(((R)-1-(3- (difluoromethyl)-2- fluorophenyl)ethyl)amino)-7-methoxy-2- methylpyrido[2,3-d]pyrimidin-6- yl)cyclobutyl)oxetane-3-carboxamide::US11648254, Compound 125

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1[C@@H]1C[C@@H](C1)NC(=O)C1COC1

InChI Key InChIKey=OBFYYSHICGZXSV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602217   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602217(US11648254, Compound 125 | N-((1S,3s)-3-(4-(((R)-1...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent