BDBM602213 (R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)-7-methoxy-2-methyl- 6-(piperidin-4-yl)pyrido[2,3-d]pyrimidin- 4-amine::US11648254, Compound 121

SMILES COc1nc2nc(C)nc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1CCNCC1

InChI Key InChIKey=DHCKRSDVXBONAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602213   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602213(US11648254, Compound 121 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent