BDBM602211 (R)-N-(1-(3-(difluoromethyl)-2- fluorophenyl)ethyl)-6-(1-ethylpiperidin- 4-yl)-7-methoxy-2-methylpyrido[2,3- d]pyrimidin-4-amine::US11648254, Compound 119

SMILES CCN1CCC(CC1)c1cc2c(N[C@H](C)c3cccc(C(F)F)c3F)nc(C)nc2nc1OC

InChI Key InChIKey=UJTAVWFLDBOCAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602211   

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602211(US11648254, Compound 119 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
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