BDBM601683 US11639355, Example 5

SMILES COc1ncc(-c2nc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2)c2cc3OCOc3c(F)c2)c(OC)n1

InChI Key InChIKey=AUYPDCJTVVOMAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601683   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Luoxin Pharmaceutical (Shanghai)

US Patent
LigandPNGBDBM601683(US11639355, Example 5)
Affinity DataIC50: 1.12nMAssay Description:In the present disclosure, the enzyme level activity the compounds is detected by using the MDM2/p53 protein binding experiment and using a TR-FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent