BDBM601494 2-(5-Chloropyridin-3- yl)-N-[(3S)-9-fluoro-2- oxo-5-phenyl-1,3- dihydro-1,4- benzodiazepin-3- yl]pyrazolo[1,5- a]pyrimidine-3- carboxamide::US11634425, Example 28

SMILES Fc1cccc2c1NC(=O)[C@@H](NC(=O)c1c(nn3cccnc13)-c1cncc(Cl)c1)N=C2c1ccccc1

InChI Key InChIKey=BXCYRFWRZPOEEA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601494   

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601494(2-(5-Chloropyridin-3- yl)-N-[(3S)-9-fluoro-2- oxo-...)
Affinity DataEC50:  41nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetNucleoprotein(Human respiratory syncytial virus A (strain A2))
Pfizer

US Patent
LigandPNGBDBM601494(2-(5-Chloropyridin-3- yl)-N-[(3S)-9-fluoro-2- oxo-...)
Affinity DataEC50:  66nMAssay Description:Hep-G2 cells (ECACC, 85011430) were passaged in flasks and seeded in 24-well plates in DMEM containing antibiotics and supplemented with 10% FBS. Dur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent