BDBM601405 US11634410, Example 15::[(1R,5S,6R)-3-{5-chloro-6- hydroxy-2-methylazetidin-1- yl]pyrimidin-4-yl}-3- azabicyclo[3.1.0]hex-6- yl]acetic acid

SMILES C[C@H]1[C@H](O)CN1c1nc(C(F)F)c(Cl)c(n1)N1C[C@H]2[C@H](CC(O)=O)[C@H]2C1

InChI Key InChIKey=AFYWUTYXJAQJCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 601405   

TargetKetohexokinase(Human)
Pfizer

US Patent
LigandPNGBDBM601405(US11634410, Example 15 | [(1R,5S,6R)-3-{5-chloro-6...)
Affinity DataIC50: 19.1nMAssay Description:A 384-well format on a Corning 3653 assay plate is used, and monitored by UV-vis spectroscopy in continuous mode at rt. Compounds were prepared in DM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent