BDBM601386 US11634424, Compound 1::US11634424, Compound 6

SMILES COc1nc(C)ccc1-c1cc(Nc2cnc3ccn(C4CCNCC4)c3n2)n[nH]1

InChI Key InChIKey=KLZYDCQIWRPHJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 601386   

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandPNGBDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 79nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 1nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Medshine Discovery

US Patent
LigandPNGBDBM601386(US11634424, Compound 6 | US11634424, Compound 1)
Affinity DataIC50: 64nMAssay Description:The compounds of the present disclosure used in the experiments were self-prepared, and their chemical names and structural formulas were shown in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
Go to US Patent