BDBM601221 4-((S)-3-((R)-4,4-dimethyl-3-phenylpentanamido)-2-(dimethylamino)propyl)-2-fluoro-N-methylbenzamide ::US11634396, Compound 159

SMILES CNC(=O)c1ccc(C[C@@H](CNC(=O)C[C@@H](c2ccccc2)C(C)(C)C)N(C)C)cc1F

InChI Key InChIKey=QVWYWCRPQNKBMQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601221   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601221(US11634396, Compound 159 | 4-((S)-3-((R)-4,4-dimet...)
Affinity DataIC50: 3.00E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601221(US11634396, Compound 159 | 4-((S)-3-((R)-4,4-dimet...)
Affinity DataEC50:  1.65E+3nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent