BDBM601132 4-[(2S)-3-[(3R)-4,4-dimethyl-3-phenylpentanamido]-2-(dimethylamino)propyl]benzamide ::US11634396, Compound 93::US11634396, Compound 95

SMILES CN(C)[C@H](CNC(=O)C[C@@H](c1ccccc1)C(C)(C)C)Cc1ccc(cc1)C(N)=O

InChI Key InChIKey=NZJBHNHUZMYHGE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 601132   

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601132(US11634396, Compound 95 | 4-[(2S)-3-[(3R)-4,4-dime...)
Affinity DataIC50: 3.00E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601132(US11634396, Compound 95 | 4-[(2S)-3-[(3R)-4,4-dime...)
Affinity DataEC50: >3.00E+3nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601132(US11634396, Compound 95 | 4-[(2S)-3-[(3R)-4,4-dime...)
Affinity DataIC50: 3.00E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601132(US11634396, Compound 95 | 4-[(2S)-3-[(3R)-4,4-dime...)
Affinity DataEC50: <300nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent