BDBM600695 US11629146, Compound 78::US20250163068, Compound 78

SMILES Fc1cc(cnc1OCC(F)(F)F)-c1cn2c(nnc2cn1)C(F)(F)F

InChI Key InChIKey=ZPZSHDXTYXOMFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600695   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600695(US11629146, Compound 78 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+5nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600695(US11629146, Compound 78 | US20250163068, Compound ...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2025
Entry Details
Go to US Patent