BDBM600686 US11629146, Compound 49

SMILES Cc1cc(OC(F)(F)F)ccc1-c1cn2c(nnc2cn1)C(F)F

InChI Key InChIKey=MCANRQHTCQLYAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600686   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600686(US11629146, Compound 49)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
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