BDBM600685 US11629146, Compound 117::US20250163068, Compound 117

SMILES COCc1cc(ccc1OC(F)(F)F)-c1ccc2nnc(n2n1)C(F)(F)F

InChI Key InChIKey=CRRFOABOXGRRDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600685   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600685(US11629146, Compound 117 | US20250163068, Compound...)
Affinity DataIC50: 2.25E+4nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600685(US11629146, Compound 117 | US20250163068, Compound...)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2025
Entry Details
Go to US Patent