BDBM600683 US11629146, Compound 84

SMILES Fc1cc(cnc1OC1CC(F)(F)C1)-c1cn2c(nnc2cn1)C(F)(F)F

InChI Key InChIKey=RJUSZVXIXJOFFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600683   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600683(US11629146, Compound 84)
Affinity DataIC50: 8.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent