BDBM600616 US11629146, Compound 48::US20250163068, Compound 48

SMILES COc1cc(OC(F)(F)F)ccc1-c1cn2c(nnc2cn1)C(F)F

InChI Key InChIKey=WTYOADQXNNRVMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600616   

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600616(US11629146, Compound 48 | US20250163068, Compound ...)
Affinity DataIC50: 1.00E+3nMAssay Description:CYP1A2 Inhibition in Human Liver Microsomes. Pooled human liver microsomes were incubated with individual CYP, CYP1A2, isozyme-specific marker substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Praxis Precision Medicines

US Patent
LigandPNGBDBM600616(US11629146, Compound 48 | US20250163068, Compound ...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2025
Entry Details
Go to US Patent