BDBM600594 (S)-(5-((3-Methylpyridin-4-yl)methyl)-1H-imidazol-2-yl)(thiazol-5-yl)methanol and (R)-(5-((3-methylpyridin-4-yl)methyl)-1H-imidazol-2-yl)(thiazol-5-yl)methanol::US11629136, Example 30::US11629136, Example 30a

SMILES Cc1cnccc1Cc1cnc([nH]1)[C@@H](O)c1cncs1

InChI Key InChIKey=UVBHRIDAJWKMAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600594   

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600594(US11629136, Example 30a | (S)-(5-((3-Methylpyridin...)
Affinity DataIC50: 5.50E+4nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent

TargetNAD(+) hydrolase SARM1 [50-724](Human)
Nura Bio

US Patent
LigandPNGBDBM600594(US11629136, Example 30a | (S)-(5-((3-Methylpyridin...)
Affinity DataIC50: 5.50E+3nMAssay Description:Each reaction was run at a volume of 20 μL containing 50 μM compound (dissolved in DMSO; final concentration of DMSO is 1% v/v), 40 nM huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
Go to US Patent