BDBM600434 US11618753, Example 1793

SMILES Cc1ccc(cc1C(=O)Nc1ccn(Cc2ccccc2)n1)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=CFPKKAHYROXBCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600434   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM600434(US11618753, Example 1793)
Affinity DataIC50: 1.80E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent