BDBM600321 5-{4-amino-5-[(4,4-difIuoropiperidin-1-yl)methyl]pyrrolo[2,1- f][1,2,4]triazin-7-yl}-4-fluoro-N-[(3R,4S)-4-fluoro-1-(3- methylbutanoyl)pyrrolidin-3-yl]-2-methylbenzamide::US11618753, Example 1659

SMILES CC(C)CC(=O)N1C[C@H](F)[C@@H](C1)NC(=O)c1cc(-c2cc(CN3CCC(F)(F)CC3)c3c(N)ncnn23)c(F)cc1C

InChI Key InChIKey=SLNXMZIYGKBQEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600321   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM600321(US11618753, Example 1659 | 5-{4-amino-5-[(4,4-difI...)
Affinity DataIC50: 1.60E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
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