BDBM598867 5-{4-amino-5-fluoropyrrolo[2,1-f][1,2,4]triazin-7-yl}-N-(1-benzyl-1H-pyrazol-4-yl)-2-methoxypyridine-3-carboxamide::US11618753, Example 8::US11618753, Example 9

SMILES COc1ncc(cc1C(=O)Nc1cnn(Cc2ccccc2)c1)-c1cc(F)c2c(N)ncnn12

InChI Key InChIKey=IPIQCRSSOLPVLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 598867   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM598867(US11618753, Example 8 | US11618753, Example 9 | 5-...)
Affinity DataIC50: 2.70E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM598867(US11618753, Example 8 | US11618753, Example 9 | 5-...)
Affinity DataIC50: 2.10E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent