BDBM598720 5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-N-(3′-(5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1-methyl-1H-pyrazole-3-carboxamido)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)thiazole-2-carboxamide::US11613536, Example 19

SMILES Cc1c(NC(=O)c2cc(CN3CC[C@@H](O)C3)n(C)n2)cccc1-c1cccc(NC(=O)c2ncc(CN3CC[C@@H](O)C3)s2)c1C

InChI Key InChIKey=INHWLSZEHMNVQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598720   

LigandPNGBDBM598720(US11613536, Example 19 | 5-(((R)-3-hydroxypyrrolid...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
5/10/2023
Entry Details
US Patent