BDBM598719 (S)-1-(5-chloro-2-((5-cyanopyridin-3-yl)methoxy)-4-((3′-(5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)thiazole-2-carboxamido)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid::US11613536, Example 18

SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c(CN3CCCC[C@H]3C(O)=O)cc2Cl)cccc1-c1cccc(NC(=O)c2ncc(CN3CC[C@@H](O)C3)s2)c1C

InChI Key InChIKey=HBVXTZAOFQLZOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598719   

LigandPNGBDBM598719(US11613536, Example 18 | (S)-1-(5-chloro-2-((5-cya...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent