BDBM598655 2-(3,8-diazabicyclo[3.2.1]octan-8-yl)-N4-ethyl-N6-(1H-indazol-5-yl)-N4-methylpyrimidine-4,6-diamine::US11613531, Example 332

SMILES CCN(C)c1cc(Nc2ccc3[nH]ncc3c2)nc(n1)N1C2CCC1CNC2

InChI Key InChIKey=HDFVSUGROVXOIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598655   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM598655(US11613531, Example 332 | 2-(3,8-diazabicyclo[3.2....)
Affinity DataIC50: 1.20nMAssay Description:Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
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