BDBM598639 2-(3,6-diazabicyclo[3.1.1]heptan-6-yl)-N-(1H-indazol-5-yl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-amine::US11613531, Example 310

SMILES C1C2CNCC1N2c1nc2CNCc2c(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=IUWVSZGHZUDCHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598639   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM598639(US11613531, Example 310 | 2-(3,6-diazabicyclo[3.1....)
Affinity DataIC50: 3.80nMAssay Description:Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
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