BDBM598093 (+1-)-trans-3-Fluoro-1-(oxetan-3-yl)piperidin-4-yl (8-amino-7-fluoro-6-(8-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-yl)isoquinolin-3-yl)carbamate ::US11612606, Compound 445ab

SMILES Cc1c2NCCOc2ncc1-c1cc2cc(NC(=O)O[C@H]3CCN(C[C@@H]3F)C3COC3)ncc2c(N)c1F

InChI Key InChIKey=PUZJMCORUGPHLG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598093   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM598093(US11612606, Compound 445ab | (+1-)-trans-3-Fluoro-...)Copy SMILESCopy InChI

Affinity DataKi: <0.0130nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/9/2023
Entry Details
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