BDBM597867 US11608330, Example 90

SMILES NCc1ncc(s1)S(=O)(=O)c1ccc2ccccc2n1

InChI Key InChIKey=IEWXIYMPLDUSHZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 597867   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Pig)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM597867(US11608330, Example 90)
Affinity DataIC50: 1.40E+3nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM597867(US11608330, Example 90)
Affinity DataIC50: 770nMAssay Description:LOX enzyme was obtained from pig skin by the method of Shackleton et al 1990.Assay Plates:Black, flat bottom 96 well platesProcedure:1. Dilute LOX en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetLysyl oxidase homolog 2(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM597867(US11608330, Example 90)
Affinity DataIC50: 90nMAssay Description:MAO-Glo Assay Kit: Promega, Cat No. V1402MAO-A Enzyme: Promega, Cat No. V1452Clorgyline: Sigma, Cat No. M3778 (50 mg)Assay Plates:96 well white polys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetAmine oxidase [flavin-containing] A(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM597867(US11608330, Example 90)
Affinity DataIC50: 1.00E+5nMAssay Description:MAO-B Enzyme: Sigma, Cat No. M7441Deprenyl: Sigma, Cat No. M003Assay Plates: 96 well white polystyrene, flat bottom plates, no lid: Fisher, Cat No. D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetAmine oxidase [flavin-containing] B(Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM597867(US11608330, Example 90)
Affinity DataIC50: 1.00E+5nMAssay Description:Promega ROS-Glo H2O2 Assay Kit, 50 ml. Cat No. G8821Inhibitors (Test compounds):10 mM stock diluted to 10, 3, 1, 0.3, 0.1, 0.03, 0.01, 0.003, 0.001, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent