BDBM597814 (S)—N-(5-Cyano-4-((tetrahydrofuran-3-yl)amino)pyridin-2-yl)-7-formyl-6-((N-methyltetrahydro-2H-pyran-4-carboxamido)methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11608332, Example 99

SMILES CN(Cc1cc2CCCN(C(=O)Nc3cc(N[C@H]4CCOC4)c(cn3)C#N)c2nc1C=O)C(=O)C1CCOCC1

InChI Key InChIKey=LHYFJOQXFQWPAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597814   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597814(US11608332, Example 99 | (S)—N-(5-Cyano-4-((t...)
Affinity DataIC50: 1.95nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597814(US11608332, Example 99 | (S)—N-(5-Cyano-4-((t...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent