BDBM597806 N-(5-Cyano-4-(((S)-1-methoxypropan-2-yl)amino)pyridin-2-yl)-7-formyl-6-(((R)—N-methyltetrahydrofuran-2-carboxamido)methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11608332, Example 92

SMILES COC[C@H](C)Nc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)[C@H]4CCCO4)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=GHESRTKBLMSFEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597806   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597806(US11608332, Example 92 | N-(5-Cyano-4-(((S)-1-meth...)
Affinity DataIC50: 9.01nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597806(US11608332, Example 92 | N-(5-Cyano-4-(((S)-1-meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent