BDBM597782 (R)-6-((1-Acetyl-N-methylpyrrolidin-2-carboxamido)methyl)-N-(5-cyano-4-((2-m ethoxyethyl)amino)pyridin-2-yl)-7-formyl-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11608332, Example 10

SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)[C@H]4CCCN4C(C)=O)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=WPPFSXSPXPNFAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597782   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597782(US11608332, Example 10 | (R)-6-((1-Acetyl-N-methyl...)
Affinity DataIC50: 1.88nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597782(US11608332, Example 10 | (R)-6-((1-Acetyl-N-methyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent