BDBM597777 N-(5-Cyano-4-(dimethylamino)pyridin-2-yl)-7-formyl-6-((N-methyltetrahydrofuran-2-carboxamido)methyl)-3,4-dihydro-1,8-naphthyridin-1(2H)-carboxamide::US11608332, Example 4

SMILES CN(C)c1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)C4CCCO4)c(C=O)nc23)ncc1C#N

InChI Key InChIKey=SSJUVDCYSLWUFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597777   

TargetFibroblast growth factor receptor 4(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597777(US11608332, Example 4 | N-(5-Cyano-4-(dimethylamin...)
Affinity DataIC50: 4.54nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR4 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Jiangsu Hansoh Pharmaceutical Group

US Patent
LigandPNGBDBM597777(US11608332, Example 4 | N-(5-Cyano-4-(dimethylamin...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this experiment, the inhibitory effect of the compounds on FGFR1 kinase activity was tested by a fluorescence resonance energy transfer (TR-FRET) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent