BDBM597767 US11608319, Compound 13

SMILES NCC(C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1ccc(C=O)cc1

InChI Key InChIKey=PZIOFOQMOZKMLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 597767   

TargetRho-associated protein kinase 1(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM597767(US11608319, Compound 13)
Affinity DataIC50: 1nMAssay Description:Table 2: Inhibitory effect of each compound synthesized above on Rho-associated protein kinase (ROCK) was tested.Method 1. 10 mM test compound was di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetMyosin light chain kinase family member 4(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM597767(US11608319, Compound 13)
Affinity DataIC50: 550nMAssay Description:Table 4: Assay for Inhibitory Effect on Myosin Light Chain Kinase 4 (MYLK-4). The experimental procedure referred to the LanthaScreen Eu Kinase Bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 19(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM597767(US11608319, Compound 13)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent