BDBM597767 US11608319, Compound 13
SMILES NCC(C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1ccc(C=O)cc1
InChI Key InChIKey=PZIOFOQMOZKMLO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 597767
Affinity DataIC50: 1nMAssay Description:Table 2: Inhibitory effect of each compound synthesized above on Rho-associated protein kinase (ROCK) was tested.Method 1. 10 mM test compound was di...More data for this Ligand-Target Pair
TargetMyosin light chain kinase family member 4(Human)
Industrial Technology Research Institute
US Patent
Industrial Technology Research Institute
US Patent
Affinity DataIC50: 550nMAssay Description:Table 4: Assay for Inhibitory Effect on Myosin Light Chain Kinase 4 (MYLK-4). The experimental procedure referred to the LanthaScreen Eu Kinase Bindi...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 19(Human)
Industrial Technology Research Institute
US Patent
Industrial Technology Research Institute
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:Table 5: The experimental procedure referred to the Z′-LYTE Screening Protocol and Assay Conditions provided by ThermoFisher Scientific. C-1. M...More data for this Ligand-Target Pair