BDBM597756 US11608319, Compound 4

SMILES NCC(Oc1ccccc1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=GRUGEVFPQKTSMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597756   

TargetRho-associated protein kinase 1(Human)
Industrial Technology Research Institute

US Patent
LigandPNGBDBM597756(US11608319, Compound 4)
Affinity DataIC50: 5.5nMAssay Description:Table 2: Inhibitory effect of each compound synthesized above on Rho-associated protein kinase (ROCK) was tested.Method 1. 10 mM test compound was di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent