BDBM597682 US11603377, Compound 3

SMILES COCCOCCS(=O)(=O)N[C@@H]1C[C@H]2CC[C@H](C)[C@](O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(CC(=O)C(C)\C=C(C)\C(O)C(OC)C(=O)C(C)CC\C=C\C=C\C=C1/C)[C@H](C)C[C@@H]1CC[C@@H](OCCCO)[C@@H](C1)OC

InChI Key InChIKey=QEKYPJBEXZLPAY-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 597682   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM597682(US11603377, Compound 3)
Affinity DataKd:  0.650nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
Go to US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM597682(US11603377, Compound 3)
Affinity DataKd: >100nMAssay Description:Biotinylated avi-FKBP51 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
Go to US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM597682(US11603377, Compound 3)
Affinity DataKd: >800nMAssay Description:Biotinylated avi-FKBP12 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
Go to US Patent

TargetPeptidyl-prolyl cis-trans isomerase FKBP5(Human)
Aeovian Pharmaceuticals

US Patent
LigandPNGBDBM597682(US11603377, Compound 3)
Affinity DataKd: >800nMAssay Description:Biotinylated avi-FKBP51 was immobilized on a streptavidin chip (Cytiva Series S SA) using a Biacore 8K or 8 k+ (Cytiva). To achieve an immobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
Go to US Patent