BDBM597616 US11597746, Compound 21

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@@H]3[C@@H](COS(=O)(=O)N[C@H]2[C@H]1F)O[C@H]([C@@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=LZBUIKWCHBNELI-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597616   

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM597616(US11597746, Compound 21)
Affinity DataIC50: 130nMAssay Description:The assay was run in 1536-well plates in a total volume of 8 μL per well by adding 8 nM [3H]-2′3′-cGAMP and 40 nM biotin-STING prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent