BDBM597591 US11597746, Compound 44

SMILES Nc1nc(N)c2ncn([C@@H]3O[C@@H]4COP([O-])(=O)O[C@@H]5[C@@H](CNS(=O)(=O)O[C@H]4[C@H]3F)O[C@H]([C@@H]5F)n3cnc4c(N)ncnc34)c2n1

InChI Key InChIKey=POSFELJMCORMSW-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597591   

TargetStimulator of interferon genes protein(Human)
Janssen Biotech

US Patent
LigandPNGBDBM597591(US11597746, Compound 44)
Affinity DataIC50: 1.44E+4nMAssay Description:The assay was run in 1536-well plates in a total volume of 8 μL per well by adding 8 nM [3H]-2′3′-cGAMP and 40 nM biotin-STING prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
Go to US Patent