BDBM597266 ((5R,9S)-3-(3,5-Dichlorophenyl)-2-methyl-4,5,6,7,8,9-hexahydro- 2H-5,9-epiminocycloocta[c]pyrazol-10-yl)(quinoxalin-6- yl)methanone;::US11597728, Example 153

SMILES Cn1nc2[C@H]3CCC[C@@H](Cc2c1-c1cc(Cl)cc(Cl)c1)N3C(=O)c1ccc2nccnc2c1

InChI Key InChIKey=VVENXFMCTKYVOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597266   

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM597266(((5R,9S)-3-(3,5-Dichlorophenyl)-2-methyl-4,5,6,7,8...)
Affinity DataIC50: 1.19nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
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