BDBM597135 US11597728, Example 21::racemic-(1-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)((5R,9S)-2- methyl-3-phenyl-4,5,6,7,8,9-hexahydro-2H-5,9- epiminocycloocta[c]pyrazol-10-yl)methanone;

SMILES Cn1ccc2c(ccnc12)C(=O)N1C2CCCC1c1nn(C)c(c1C2)-c1ccccc1

InChI Key InChIKey=NUBCSOOBBRZRJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597135   

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM597135(racemic-(1-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)((...)
Affinity DataIC50: 0.290nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2023
Entry Details
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