BDBM596379 US11596633, Compound C

SMILES COc1nc(c(N)nc1N1CCC2(CO[C@@H](C)[C@H]2N)CC1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=UPUAZCZXWGHGPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596379   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM596379(US11596633, Compound C)
Affinity DataIC50: 1.29nMAssay Description:Objective: To demonstrate the inhibition of SHP2 activity with Compounds A, B, and C. Without wishing to be bound by theory, SHP is allosterically ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
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